The first sod will be turned on a major new manufacturing facility in Athenry later today (Fri).
The US multinational company, Dexcom, is locating its first European plant in the Galway town and 1,000 permanent new jobs are set to be created.
Dexcom manufactures high-tech diabetes equipment.
The company is headquartered in California and operates manufacturing plants in Arizona and Malaysia.
It will build a four storey manufacturing facility in Athenry, located at an IDA site on the western edge of the town. The plans include an outdoor landscaped plaza and a 2.1km nature trail, as well as new access roads and pedestrian footpaths and crossings.
500 jobs will be created during the construction phase.
The project is estimated to represent an investment of €300m to the area, over a five year period.