The Doocastle road outside Charlestown remains closed to traffic this evening.
A man has been taken to Mayo University Hospital following the single vehicle collision which happened at around 11:15am this morning.
Gardai are advising that the road will remain closed for the next number of hours and diversions are in place.
Traffic intending to head North along the L-1305 are being diverted at Cloonmore and re-joining the L-1305 at Cloonlarhan via Carracastle/Cloontia.
Traffic intending to head South along the L-1305 to Charlestown are being diverted at Cloonlarhan via Cloontia/Carracastle.