Mayo has the lowest 7-day incidence rate of Covid-19 in Connacht, according to the latest data from the HPSC.
The rate of infection in the county in the last week of 2021 was 1,172 per 100,000 people, accounting for 1,530 cases of the virus.
This is lower than the national figure of 1,366 per 100,000 over the same timeframe.
The median age of those infected in Mayo was 28.
Elsewhere across the province Galway had the highest rate of infection at 1524 per 100,000 accounting for 3.933 cases.
In Roscommon the rate was 1,379 per 100,000, which translates into 890 infections.
The median age of those infected in Galway and Roscommon over the period was 29.
And in Leitrim the rate was 1,295 per 100,000, resulting in 2438 cases of the virus, with a median age of 30.
Westmeath had the highest rate of infection nationally over Christmas period at more than double the national average.
It had 3,056 cases per 100,000 people in the last week of 2021.
Clare had the second highest rate, at 1,974, followed by Kilkenny at 1,855 and Longford at 1,820.
The lowest incidence rate was in Kerry at 885 cases per 100,000 of the population, followed by Wexford, Waterford and Cavan.