Gardaí and emergency services attended the scene of a two vehicle collision this evening, at Knockanillaun in Ballina.
The collision, involving a van and a car, occurred on the N59 road at approximately 5.30pm.
The four occupants of the car, all male, were taken to Mayo University Hospital for treatment of injuries that are described as serious, but not believed to be life-threatening.
The driver of the van was unharmed.
A technical examination of the scene has since been completed and the road has fully re-opened.