There's been an 8 per cent decrease in Covid-19 cases over the past five days.
6,206 new infections have been reported during that period - compared to 6,735 in the previous five days.
1,314 new cases were confirmed yesterday.
Mayo now has the 3rd highest 7-day incidence rate of the virus nationally, after 379 new cases of the virus were confirmed in the county over the past week.
Latest data shows the national 7-day incidence rate is almost 190 per 100,000 people - it's 290 in Mayo, and higher again in Donegal and Louth.
Galway, Sligo and Roscommon all have 7-day rates above the national average also.
Galway has recorded 724 new cases of the virus over the past week, with 147 in Sligo and 138 cases in Co Roscommon.
The Chief Medical Officer is encouraging all people who are eligible for vaccination but have not yet been vaccinated to do so "as soon as they can".
Dr Tony Holohan said that "full vaccination is the best protection" against Covid-19, including from strains such as the Delta variant.
He said that while no vaccine is 100% effective, breakthrough infections that occur are generally much less severe, and they are associated with less risk of hospitalisation.