The five-day moving average of Covid-19 cases has increased by over 300 per cent over the past month.
Deputy chief medical officer, Ronan Glynn, says it has risen from 300 to 1,223 during that period.
Yesterday evening 1,378 new cases were reported - the highest daily total since January 30th.
Galway currently has the 4th highest rate of the virus nationally, after Donegal, Louth and Dublin.
Galway, Roscommon and Sligo all have 14-day rates above the national average, which now stands at 245 per 100,000 people.
Mayo's 14-day rate is now 219 per 100,000 - after the county confirmed 286 new cases of the virus over the past fortnight, with 663 new cases in Co Galway in that period.