There's no stopping a Delta wave of Covid-19 in Ireland, according to the Chief Medical Officer, Dr Tony Holohan.
The proportion of cases of the strain has risen to an estimated to be as high as 70 percent.
The National Public Health Emergency Team is predicting significant transmission of the virus in the coming months.
It comes as Ireland's death toll from Covid-19 reached 5,000 yesterday, following confirmation of two further deaths. 448 new cases of covid-19 were also reported last evening.
The reproductive rate of the virus now stands somewhere between 1 and 1.2.
Donegal has the highest 14-day incidence rate in the country, with 250 cases per 100,000 people.
Sligo and Roscommon are also in the top 5 counties - Sligo's incidence rate of the virus is 160 and Roscommon is 154 cases per 100,000.
Mayo has the second-lowest incidence rate nationally, at 29 cases per 100,000 people.
The 14-day rate nationally is 101 cases per 100,000.
Due to the high incidence rate in the Roscommon Town region, the HSE is opening a walk-in pop-up test centre in the Roscommon Arts Centre next Monday and Tuesday.
The centre will be open from 11am to 5pm on both days.
A walk-in Covid-19 test centre has also opened in Galway city centre.
The test centre is located at a former tourist office in Eyre Square, and is open from 10am to 5pm, seven days a week, as part of the ongoing effort to contain the spread of the virus.