104 patients with Covid-19 were being treated in public hospitals last night - the lowest number since the end of September.
It's a fall of more than 22 percent in a week, while there are 32 people with the virus in ICU.
The five-day moving average of Covid-19 cases has dropped by 12 percent in the same period.
The Department of Health confirmed 381 new cases of the disease yesterday, and no further deaths.
There were 11 new cases of the virus in Galway, 5 in Roscommon, less than 5 in Mayo and no new cases confirmed in either Leitrim or Sligo.
It comes as there's a split among health experts over the usage of home antigen tests after Lidl started to sell packs of five last week.
The Chief Medical Officer Dr Tony Holohan is warning people against using them, while immunologist Luke O'Neill has praised the retailer and says the HSE should have issued guidance on their usage.
Professor Gerry Killeen from UCC believes the home is not the correct environment for antigen testing: