56 fewer people were in public hospitals with Covid-19 last night, compared with Sunday night.
The number dropped to 310 last night - from 366 three days earlier.
Latest figures show there are 75 patients with the virus in intensive care.
All hospitals across this region have seen a drop in the number of Covid patients in recent days, except Sligo University Hospital.
Last night's figures from the HSE show 7 Covid patients at Mayo University Hospital - down from 12 on Sunday, 3 at Galway University Hospital - down 1 - and 4 at Portiuncla Hospital in Ballinasloe.
There are now 15 Covid patients at Sligo University Hospital - the highest number across the region, and up from 11 on Sunday.