The pharmaceutical company AbbVie is set to close its Galway operation with the loss of around 75 jobs.
RTE is reporting this evening that he facility, in the Knocknacarra area of the city, has had a number of owners since it was established in 2016.
Initially run by Zeltiq, the plant was acquired by Allergan in 2017. Last year, AbbVie's takeover of Allergan was formally approved by US authorities.
The Galway site served as a manufacturing hub for a product designed to reduce body fat.
It is understood operations there will cease by the end of the year.
AbbVie says it will engage with workers and that redeployment opportunities will be offered to those who wish to avail of them.
The company has other facilities in Sligo, Cork and Dublin with former Allergan owned operations in Westport and Dublin.