The head of the HSE says Ireland's health system is under 'increasing strain'.
Paul Reid's comments come as 1,421 people are now being treated in hospital for Covid-19, while 121 are in intensive care.
There are 69 people with the virus being treated at Mayo University Hospital, up 6 on the previous daily update.
Elsewhere across the region there are 75 patients with the disease in Galway, 30 in Sligo and 11 at the Portiuncula.
There are no Covid-19 patients on critical care beds in Mayo, according to the figures from the HSE as of 8pm yesterday evening.
While there are 8 Covid patients on critical care beds in Galway, 3 in Sligo and 1 at the Portiuncula Hospital.
High infection rates among healthcare staff has raised concern that ICU surge capacity could be impacted, leaving doctors with tough ethical choices.
Meanwhile it's reported some hospital staff have been asked to conserve oxygen over an expected influx in admissions in the coming days.
Professor Sam McConkey from the Royal College of Surgeons says the situation is worrying.