Fears over the spread of coronavirus have already hit some major sporting fixtures, and St Patrick's Day parades across the country are also being cancelled.
Businesses in towns and villages across the region will be hit as a result of the cancellations, while the hotel industry is beginning to feel the pinch.
Darren Madden of the Clew Bay Hotel in Westport is chairman of the Mayo branch of the Irish Hotels Federation.
He says the number of international tourists will be down this year, due to Covid 19.
However, he says hotels can offer good value to Irish customers to enjoy "staycations".
Mr Madden says hotels have introduced the necessary practices during the current crisis, and says it's important that hotels can keep their staff employed during this uncertain time, so they can continue to deliver a quality service once this coronavirus crisis is over.