A Mayo TD is calling on the Ministers for Health & Finance to work with SIPTU to try and avoid tomorrow' strike by health support staff.
10,000 hospital staff will take part in a 24-hour strike tomorrow, with further strikes planned for the coming weeks, in a row over pay.
Healthcare assistants, porters and catering staff are among the SIPTU workers taking the action.
Mayo, Galway, Sligo and Roscommon University Hospitals will be impacted by the strike, as well as Merlin Park and Portiuncla Hospitals.
Thousands of patients scheduled for surgery could have their appointments cancelled tomorrow, and there are also fears that some hospitals won't be able to provide regular meals and hot food to patients.
The HSE says contingency plans are in place, but warns the strike will have a significant impact on services if it goes ahead.
Mayo Fianna Fail Deputy Lisa Chambers says the hospital support staff are frustrated, because the Government is failing to follow through on a commitment made in advance of carrying out a job evaluation scheme.
And Mayo Sinn Fein Senator Rose Conway-Walsh has also called for the implementation of pay agreements for the hospital support staff, who she says "hold our health service together".
Senator Conway-Walsh says these workers are on some of the lowest wages within the healthcare system, and should not have to wait so long for pay that's due to them.