The Chief Medical Officer has warned Ireland is now dealing with 'widespread' community transmission of Covid-19.
Dr Tony Holohan says it has become 'a whole population issue' and has appealed to every individual, family, household and workplace to act on public health advice.
It comes as three further deaths were confirmed last night, along with a further 811 new cases of the virus - spread across all counties.
Cavan has overtaken Donegal as the newest hotspot, after 22 new cases gave it an incidence of over 412 cases per 100,000 in the last 14 days.
There were 9 new cases in Mayo yesterday, 39 in Galway, 8 in Sligo and less than 5 in both Roscommon and Leitrim.
In terms of the 14-day incidence rate of the virus in Connacht, Sligo has overtaken Roscommon and now has a rate of 187.
Roscommon is at 182 cases per 100,000 people, Galway is next at 165, with Leitrim at 137 and Mayo remains the only Connacht county with a 14-day incidence rate of less than 100 - it's now at just over 80.
105 new cases of the virus have been confirmed in Mayo in the past 2 weeks, compared to 427 in Galway, 123 in Sligo and 118 in Roscommon.
The latest HSE update shows 230 patients in hospital with confirmed Covid-19 - this includes 5 patients at Mayo University Hospital, 8 at UHG and one at both Sligo and Portiuncla Hospitals.