Senator Catherine Noone, a native of Claremorris, has been added to the Fine Gael election ticket in Dublin Bay North.
Senator Noone will run alongside Education Minister Richard Bruton after a meeting of the party's executive council earlier this week.
Dublin Bay North was one of the toughest battlegrounds in the country in 2016 - but Ms Noone said she is looking forward to the challenge.
Other TDs in the area include the Minister for Disabilities Finian McGrath and Fianna Fáil's Seán Haughey.
Catherine Noone, who ran alongside Leo Varadkar in Dublin West last time, said her new constituency is "a large and increasingly diverse constituency affected by a wide range of issues".
Senator Noone, Deputy Leader of the Seanad, recently chaired the Oireachtas Committee on the Eighth Amendment which published its recommendations last December ahead of the constitutional amendment in May.